Prediction of Amyloid-β Pathology in Amnestic Mild Cognitive Impairment with Neuropsychological Tests
نویسندگان
چکیده
منابع مشابه
The Role of Neuropsychological Function Tests in Predicting Amnestic Mild Cognitive Impairment in the Elderly
Background: Various studies have documented age-related changes in cognitive abilities and neural basis. Objectives: To investigate the role of neuropsychological function tests in predicting amnestic mild cognitive impairment in the elderly. Materials & Methods: In this cross-sectional study with a correlational design, the study population included elderly people over 60 years old residing ...
متن کاملComparison of performance in neuropsychological tests in amnestic Mild Cognitive Impairment and Alzheimer’s disease patients
Mild Cognitive Impairment (MCI) can be an intermediate state between normality and dementia in some patients. An early diagnosis, through neuropsychological assessment, could identify individuals at risk of developing dementia. Objective To verify differences in performance on neuropsychological tests among controls, amnestic MCI (aMCI) and Alzheimer's disease (AD) patients. Methods Sixty-e...
متن کاملNeuropsychological Testing Predicts Cerebrospinal Fluid Amyloid-β in Mild Cognitive Impairment.
BACKGROUND Psychometric tests predict conversion of mild cognitive impairment (MCI) to probable Alzheimer's disease (AD). Because the definition of clinical AD relies on those same psychometric tests, the ability of these tests to identify underlying AD pathology remains unclear. OBJECTIVE To determine the degree to which psychometric testing predicts molecular evidence of AD amyloid patholog...
متن کاملProspective memory in amnestic mild cognitive impairment.
Individuals with amnestic mild cognitive impairment (aMCI) often complain of difficulty remembering to carry out intended actions, consistent with findings of impaired prospective memory (PM) in this population. In this study, individuals with aMCI (N = 27) performed worse than healthy controls (N = 27) on the Memory for Intentions Screening Test (Raskin, 2004), including on time- and event-bas...
متن کاملDifferences in Functional Brain Connectivity Alterations Associated with Cerebral Amyloid Deposition in Amnestic Mild Cognitive Impairment
Despite potential implications for the early detection of impending Alzheimer's disease (AD), very little is known about the differences of large-scale brain networks between amnestic mild cognitive impairment (aMCI) with high cerebral amyloid-beta protein (Aβ) deposition (i.e., aMCI+) and aMCI with no or very little Aβ deposition (i.e., aMCI-). We first aimed to extend the current literature o...
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ژورنال
عنوان ژورنال: Journal of Alzheimer's Disease
سال: 2012
ISSN: 1875-8908,1387-2877
DOI: 10.3233/jad-2012-121315